Birth weight (grams)

Gestational age (weeks)

Birth month

Number of living siblings at delivery

Maternal age at delivery (years)

5-minute Apgar score

Infant sex

Birth of single or multiple infant(s)

Maternal region of residence at delivery

Maternal education at delivery

Prenatal smoking

Delivery method

Continuous positive airway pressure (CPAP) during infant birth hospitalization

Ventilation during infant birth hospitalization

Infant Down syndrome

Infant bronchopulmonary dysplasia

Infant cyanotic heart disease

Infant congenital anomalies of the respiratory sytem

Length of infant birth hospitalization

This risk prediction tool is based on the following article:

Snyder BM, Achten NB, Gebretsadik T, Wu P, Mitchel EF, Escobar G, Bont LJ, and TV Hartert (2024). Personalized infant risk prediction for severe respiratory syncytial virus lower respiratory tract infection requiring intensive care unit admission. Open Forum Infect Dis, 11(3):ofae077. PMID 38481426

Details on Study Methodology:

Findings are based on a Medicaid population
Infants who received RSV immunoprophylaxis during the first year of life were excluded
Severe RSV LRTI was defined as acute bronchiolitis or RSV pneumonia hospitalization requiring Intensive Care Unit (ICU) admission occurring any time after birth hospitalization within the first year of life
Predictors were ascertained within the first 30 days of life from healthcare encounters and linked birth and death certificates

Disclaimer:

This tool is currently for research purposes only. Cost-effective analyses, decision curve analyses, and validation in external populations are needed prior to clinical implementation to determine optimal use. (Updated May 2024)

For questions about the design and analysis of the study, contact Tina Hartert (tina.hartert@vumc.org). For questions about the web application, contact Tebeb Gebretsadik (tebeb.gebretsadik@vumc.org).